Kukhtevich A V, Ianushkevich T N, Adnoral S A, Gitel' E P
Ter Arkh. 1994;66(10):33-5.
Renal function was assessed in 8 males at reproductive age suffering from lupus nephritis (LN). Normal renal function was registered in 5 patients, hypofunction in 3 males. Endocrinological examinations (evaluation of secondary sexual characters, of hypophyseal and sex hormone profile, sexological questionnaires, spermograms) failed to distinguish significant differences between SLE males and renal patients without SLE suffering from hypogonadism (13 males with uremic hypogonadism, 10 males with azoospermia induced by cytostatics). Endocrinological changes revealed may result from uremia and immunodepressive therapy. In 5 patients these abnormalities were corrected by parlodel and zinc sulfate. The authors came to the conclusion that feminization is not universal in LN males.
对8名患有狼疮性肾炎（LN）的育龄男性进行了肾功能评估。5名患者肾功能正常，3名男性肾功能减退。内分泌检查（对第二性征、垂体和性激素谱的评估、性学问卷、精液分析）未能区分狼疮男性患者与无狼疮的性腺功能减退肾病患者（13名患有尿毒症性性腺功能减退的男性、10名因细胞抑制剂导致无精子症的男性）之间的显著差异。所揭示的内分泌变化可能是由尿毒症和免疫抑制治疗引起的。在5名患者中，这些异常通过溴隐亭和硫酸锌得到了纠正。作者得出结论，女性化在LN男性中并非普遍现象。
