Sidorov I S, Guriev T D
Ter Arkh. 1994;66(10):55-7.
48 females with uterine endometriosis stage 1 and 2, 26 female with mild and moderate external endometriosis and 9 females with external in combination with internal endometriosis with the disease duration from 6 months to 10 years were given danazol in doses 200-400 mg/day for 6 months. The effect of the treatment proved to be very high: 37 patients were cured, 14 improved, 3 got pregnant. 11 patients needed the second treatment course. Side effects were rare. Depressed hyperactive menstrual cycle normalized quickly. It is inferred that danazol doses 200-400 mg/day are adequate for induction of complete or partial responses in internal and external endometriosis.
48例1期和2期子宫内异症女性、26例轻度和中度外在性内异症女性以及9例合并内在性和外在性内异症女性(病程6个月至10年)接受了达那唑治疗,剂量为每日200 - 400毫克,疗程6个月。治疗效果非常显著:37例患者治愈,14例改善,3例怀孕。11例患者需要第二个疗程治疗。副作用罕见。月经周期紊乱迅速恢复正常。推断每日200 - 400毫克达那唑剂量足以诱导内在性和外在性内异症产生完全或部分反应。