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使用简化的选择性脑灌注技术对主动脉弓动脉瘤进行外科治疗。

Surgical treatment of aneurysms of the aortic arch using a simplified selective cerebral perfusion technique.

作者信息

Aoyagi S, Akashi H, Kubota Y, Momosaki M, Tayama K, Hanamoto Y, Oryoji A, Kosuga K, Oishi K

机构信息

Second Department of Surgery, Kurume University School of Medicine, Japan.

出版信息

Thorac Cardiovasc Surg. 1994 Oct;42(5):279-84. doi: 10.1055/s-2007-1016505.

Abstract

Between April 1989 and October 1993, 35 patients underwent aortic arch reconstruction for aneurysms using cardiopulmonary bypass (CPB) with selective cerebral perfusion (SCP). Of the 35 patients, the initial 19 (Group P) consecutively received simplified SCP (partial brachiocephalic perfusion; PBP), and the next 16 (Group S) were consecutively treated with standard SCP. For cerebral protection, blood was supplied to the right axillary artery in Group P, and to the right axillary and the left common carotid arteries in Group S. The aneurysms was aortic dissection in 24 patients, and was secondary to arteriosclerosis in the remaining 11. Partial replacement of the aortic arch together with the ascending aorta was the most commonly performed procedure in both groups. The cardiopulmonary bypass time and the cardiac arrest time were not significantly different between the two groups. The overall cerebral perfusion time was significantly longer in Group S (100 min) than in Group P (65 min); however, when 2 patients with an accidental prolongation of the cerebral perfusion time in Group S were excluded, there was no significant difference in the cerebral perfusion time between the two groups. Early death occurred in 3 patients (15.8%) in Group P, and 2 patients (12.5%) in Group S, however, there were no deaths related to the selective cerebral perfusion technique, and there were no late deaths in either group. Cerebral complications were seen in 1 patient in each group (6.3% vs. 6.7%, not significant). These results suggest that the simplified SCP (PBP) under hypothermic CPB provides as satisfactory cerebral protection as standard SCP, so long as the patency of the circle of Willis is confirmed.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1989年4月至1993年10月期间,35例患者接受了使用体外循环(CPB)和选择性脑灌注(SCP)进行的主动脉弓动脉瘤重建术。在这35例患者中,最初的19例(P组)连续接受简化SCP(部分头臂灌注;PBP),接下来的16例(S组)连续接受标准SCP治疗。为保护大脑,P组将血液供应至右腋动脉,S组则供应至右腋动脉和左颈总动脉。24例患者的动脉瘤为主动脉夹层,其余11例继发于动脉硬化。两组最常进行的手术均为部分主动脉弓置换术加升主动脉置换术。两组的体外循环时间和心脏停搏时间无显著差异。S组的总体脑灌注时间(100分钟)明显长于P组(65分钟);然而,排除S组中2例脑灌注时间意外延长的患者后,两组的脑灌注时间无显著差异。P组有3例患者(15.8%)早期死亡,S组有2例患者(12.5%)早期死亡,然而,没有与选择性脑灌注技术相关的死亡,两组均无晚期死亡。两组各有1例患者出现脑部并发症(6.3%对6.7%,无显著差异)。这些结果表明,在低温CPB下,简化SCP(PBP)与标准SCP一样能提供令人满意的脑保护,只要确认 Willis 环通畅。(摘要截断于250字)

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