Christensen L D, Dickmeiss E
Department of Clinical Immunology, Rigshospitalet, University Hospital, Copenhagen, Denmark.
Vox Sang. 1994;67(3):267-71. doi: 10.1111/j.1423-0410.1994.tb01249.x.
A newly developed filter for prestorage leucocyte depletion of platelet concentrates (PC) was studied. The filter is designed for leucocyte depletion during the preparation of the pool PC from platelet rich buffy coats. In all the leucocyte depleted PC (LD-PC) leucocyte depletion was satisfactory. 19 of 20 units of LD-PC had a leucocyte content below 3 x 10(5) per PC and 1 contained 8 x 10(5) leucocytes. The standard PC contained 2.53 x 10(8) (0.87 x 10(8)-15.3 x 10(8); n = 20) leucocytes per PC (median and range). The quality of the LD-PC was evaluated by measuring platelet activation, platelet morphology, and pre- and poststorage pH. There were no differences in any of the parameters studied.
对一种新开发的用于血小板浓缩物（PC）储存前白细胞去除的过滤器进行了研究。该过滤器设计用于在从富含血小板的血沉棕黄层制备混合PC的过程中去除白细胞。在所有白细胞去除的PC（LD-PC）中，白细胞去除效果令人满意。20个单位的LD-PC中有19个的白细胞含量低于每单位PC 3×10⁵，1个含有8×10⁵个白细胞。标准PC每单位PC含有2.53×10⁸（0.87×10⁸ - 15.3×10⁸；n = 20）个白细胞（中位数和范围）。通过测量血小板活化、血小板形态以及储存前后的pH值对LD-PC的质量进行了评估。在所研究的任何参数中均未发现差异。
