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[一名患者冠状动脉介入治疗期间血管壁内陷导致的假性狭窄]

[Pseudo-stenosis caused by vessel wall invagination during interventional treatment of 2 coronary vessels in a patient].

作者信息

Herrmann G, Lins M, Meissner A, Muurling S, Pospiech R, Simon R

机构信息

I. Med. Universitätsklinik C. A. U., Klinik für Kardiologie, Kiel.

出版信息

Z Kardiol. 1995 Jan;84(1):30-4.

PMID:7863711
Abstract

We report on a 59-year-old man who underwent a combined procedure of directional coronary atherectomy (DCA) and PTCA of significant lesions of the right coronary artery (RCA) and the left circumflex artery (LCX). Already after positioning of a standard guide wire in the right coronary artery a new excentric "pseudo-stenosis" was observed in the proximal part of the right coronary artery. Since the patient remained symptom free, a 7F DCA catheter was introduced to the stenotic area in the mid RCA, which led to an extension of the narrowing, involving the total segment proximal to the DCA catheter. Directional coronary atherectomy was performed without complications. Removal of the catheter, after successful DCA, and administration of intracoronary nitroglycerin did not relieve the proximal narrowing, which disappeared spontaneously after the guide wire was pulled out. During PTCA of the left circumflex using a standard guide wire and a 3.0 mm Monorail balloon catheter, a similar tight narrowing of the origin of the LCX was observed, which could also not be influenced by vasodilator drugs, but relieved after wire removal. Until now, this phenomenon has only been described for the right coronary artery. The reason underlying intimal folding is a shifting of the intimal layer against the medial layer of the vessel wall. Our observation firstly describes this phenomenon of "pseudo narrowing" in two different vessels in one patient. We, like other authors before, recommend that interventional therapy of these pseudo-lesions should be avoided.

摘要

我们报告了一名59岁男性,其接受了右冠状动脉(RCA)和左旋支动脉(LCX)严重病变的定向冠状动脉斑块旋切术(DCA)和经皮冠状动脉腔内血管成形术(PTCA)联合手术。在将标准导丝置入右冠状动脉后,即在右冠状动脉近端观察到一个新的偏心“假性狭窄”。由于患者无症状,将一根7F DCA导管插入RCA中段的狭窄区域,这导致狭窄范围扩大,累及DCA导管近端的整个节段。定向冠状动脉斑块旋切术顺利完成,无并发症。在DCA成功后拔出导管并给予冠状动脉内硝酸甘油,近端狭窄并未缓解,但在拔出导丝后狭窄自行消失。在使用标准导丝和3.0 mm单轨球囊导管对左旋支进行PTCA期间,观察到LCX起始部有类似的严重狭窄,血管扩张药物对此也无影响,但在拔出导丝后狭窄缓解。迄今为止,这种现象仅在右冠状动脉中被描述过。内膜折叠的根本原因是内膜层相对于血管壁中层发生移位。我们的观察首次描述了一名患者两条不同血管中出现的这种“假性狭窄”现象。与之前的其他作者一样,我们建议应避免对这些假性病变进行介入治疗。

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