Anguita M, Arizón J M
Section of Heart Transplantation, Spanish Society of Cardiology, Madrid, Spain.
J Heart Lung Transplant. 1994 Nov-Dec;13(6):950-7.
The first heart transplantation in Spain was performed in 1984. Since then, 950 patients had undergone heart transplantation in our country as of December 1992. Data from all these 950 patients have been reported to the Spanish National Registry of Heart Transplantation since its inception in 1989. Follow-up is complete for all patients. Mean age of recipients was 46 +/- 14 years; 86% were male patients. Almost 50% of all heart transplant procedures were performed in 1991 (232 patients, 6 per million persons) and 1992 (254 patients, 6.6 per million). Twelve centers have performed heart transplantations in Spain. Of the 950 procedures, 907 (95%) have been orthotopic, 6 (0.6%) heterotopic, 16 (1.7%) heart-lung transplantations, and 21 (2.7%) retransplantations. Mortality on waiting list was 8% in 1991 and 5.2% in 1992. Idiopathic (47%) and ischemic (37%) cardiomyopathy were the two main causes leading to transplantation. Mean recipient age has increased from 38 years in 1985 to 50 in 1992; 50% of all patients who underwent transplantation in 1992 were older than 50 years of age, with 11% older than 60 years of age. Actuarial survival was 74% at 1 year and 63% at 6 years, which is similar to that of the International Society for Heart and Lung Transplantation Registry. One-year survival increased from 61% for patients receiving transplants in 1985 to 77% for those who received transplants in 1992. One-month mortality decreased from 23% in 1985 to 12% in 1992.(ABSTRACT TRUNCATED AT 250 WORDS)
西班牙首例心脏移植手术于1984年实施。自那时起,截至1992年12月,我国已有950例患者接受了心脏移植手术。自1989年西班牙国家心脏移植登记处成立以来,这950例患者的所有数据均已上报。所有患者均有完整的随访记录。接受者的平均年龄为46±14岁;86%为男性患者。几乎50%的心脏移植手术是在1991年(232例患者,每百万人口中有6例)和1992年(254例患者,每百万人口中有6.6例)进行的。西班牙有12个中心开展了心脏移植手术。在这950例手术中,907例(95%)为原位心脏移植,6例(0.6%)为异位心脏移植,16例(1.7%)为心肺联合移植,21例(2.7%)为再次移植。1991年等待名单上的死亡率为8%,1992年为5.2%。特发性心肌病(47%)和缺血性心肌病(37%)是导致移植的两个主要原因。接受者的平均年龄从1985年的38岁增加到1992年的50岁;1992年接受移植的所有患者中有50%年龄超过50岁,其中11%年龄超过60岁。精算生存率1年时为74%,6年时为63%,与国际心肺移植学会登记处的情况相似。1年生存率从1985年接受移植患者的61%增至1992年接受移植患者的77%。1个月死亡率从1985年的23%降至1992年的12%。(摘要截取自250词)