Van Winkle L J, Kakuda D K, MacLeod C L
Department of Biochemistry, Midwestern University, Downers Grove, IL 60515.
Biochim Biophys Acta. 1995 Feb 15;1233(2):213-6. doi: 10.1016/0005-2736(94)00303-7.
Expression of putative amino acid transport proteins is usually assumed to be associated with expression of a single component of transport. It is shown in this report, however, that murine cationic amino acid transporter (mCAT) expression in Xenopus oocytes is associated in important instances with expression of more than one kinetically distinguishable transport process. Accurate knowledge of the kinetics of transport continues, therefore, to be needed to understand how transport proteins function.
通常认为假定的氨基酸转运蛋白的表达与单一转运成分的表达相关。然而,本报告表明,非洲爪蟾卵母细胞中鼠阳离子氨基酸转运体(mCAT)的表达在重要情况下与不止一种动力学上可区分的转运过程的表达相关。因此,要了解转运蛋白的功能,仍需要准确掌握转运动力学。