González A, Ros D, Pavia J
Laboratori de Biofisica i Bioenginyeria, Facultat de Medicina, Universitat de Barcelona, Spain.
J Nucl Biol Med (1991). 1994 Sep;38(3):502-7.
Renal transit time and relative renal function are the most commonly used parameters in the study of renal function. In clinical practice the determination of these two parameters is carried out either using the renal retention function or directly from the renogram. This study seeks to compare the values for the transit time and the relative function, as calculated from the renogram and from the renal retention function, in renographic studies using 131I-OIH and 99mTc-MAG3. For both tracers it was found that the estimated renal transit time from the renogram (OIH: 289 +/- 118 s, MAG3: 297 +/- 110 s) generated values that were higher than those obtained from the renal retention function (OIH: 245 +/- 85 s, MAG3: 274 +/- 97 s), with significant differences between the two estimates (p < 0.001). As regards the relative function, there were no significant differences between the estimates obtained from the renogram (58.5 +/- 8.3%) and the renal retention function (59.5 +/- 9.3%) in the case of OIH. For MAG3 the estimate obtained from the renogram (58.3 +/- 6.3%) and from the renal retention function (59.9 +/- 7.1%) were significantly different (p < 0.025).
肾通过时间和相对肾功能是肾功能研究中最常用的参数。在临床实践中，这两个参数的测定要么通过肾脏潴留功能进行，要么直接从肾图中获取。本研究旨在比较在使用¹³¹I - OIH和⁹⁹ᵐTc - MAG3的肾图研究中，通过肾图和肾脏潴留功能计算得出的通过时间和相对功能的值。对于这两种示踪剂，发现从肾图估计的肾通过时间（OIH：289±118秒，MAG3：297±110秒）产生的值高于从肾脏潴留功能获得的值（OIH：245±85秒，MAG3：274±97秒），两种估计之间存在显著差异（p < 0.⁰⁰¹）。关于相对功能，在OIH的情况下，从肾图获得的估计值（58.5±8.3%）和肾脏潴留功能获得的估计值（59.5±9.3%）之间没有显著差异。对于MAG3，从肾图获得的估计值（58.3±6.3%）和肾脏潴留功能获得的估计值（59.9±7.1%）有显著差异（p < 0.⁰²⁵）。
