Pontes J M, Leitão M C, Portela F A, Rosa A M, Ministro P, Freitas D S
Department of Gastroenterology, Coimbra University Hospital, Portugal.
Eur J Gastroenterol Hepatol. 1995 Jan;7(1):41-6.
To assess the role of endoscopic ultrasonography (EUS) in monitoring the treatment of oesophageal varices by endoscopic sclerotherapy and band ligation.
We studied 35 patients with portal hypertension undergoing elective treatment for oesophageal varices by injection sclerotherapy with absolute ethanol (group 1, n = 19) or by endoscopic variceal ligation (EVL; group 2, n = 16). All patients were examined by EUS before treatment to assess the status of their oesophago-gastric varices and the presence of collateral and perforating veins. Evaluation with EUS was repeated to confirm variceal eradication whenever endoscopy suggested successful obliteration, or to determine the reason for failure when treatment did not appear to be successful. Depending on the endosonographic findings, treatment was continued until EUS showed complete variceal eradication.
After treatment, EUS showed insufficient variceal thrombosis in six (17%) patients who appeared to have variceal eradication at endoscopy. EUS was also superior to endoscopy for diagnosing gastric varices and showed patent vessels in 26 (74%) out of 35 patients. Gastric varices observed on EUS were detected at endoscopy in only 60% of cases. Endoscopic sclerotherapy and EVL had induced characteristic changes on EUS evaluation, and oesophageal fibrosis was observed more frequently in endoscopic sclerotherapy than in EVL-treated patients.
EUS provides valuable information on the status of oesophago-gastric varices and can be used to assess the efficiency of endoscopic sclerotherapy and EVL.
评估内镜超声检查(EUS)在监测内镜硬化治疗和套扎术治疗食管静脉曲张中的作用。
我们研究了35例门静脉高压患者,这些患者接受了选择性食管静脉曲张治疗,其中19例采用无水乙醇注射硬化治疗(第1组),16例采用内镜下静脉曲张套扎术(EVL;第2组)。所有患者在治疗前均接受EUS检查,以评估食管胃静脉曲张的状况以及侧支静脉和穿通静脉的存在情况。每当内镜检查提示成功闭塞时,重复进行EUS评估以确认静脉曲张根除情况;当治疗似乎未成功时,确定失败原因。根据内镜超声检查结果,继续治疗直至EUS显示静脉曲张完全根除。
治疗后,EUS显示6例(17%)在内镜检查时看似静脉曲张已根除的患者存在静脉曲张血栓形成不足的情况。EUS在诊断胃静脉曲张方面也优于内镜检查,35例患者中有26例(74%)显示血管通畅。EUS观察到的胃静脉曲张在内镜检查中仅60%的病例被检测到。内镜硬化治疗和EVL在EUS评估中引起了特征性变化,内镜硬化治疗患者比接受EVL治疗的患者更频繁地观察到食管纤维化。
EUS提供了关于食管胃静脉曲张状况的有价值信息,可用于评估内镜硬化治疗和EVL的疗效。