Peng N J, Lai K H, Tsay D G, Liu R S, Su K L, Yeh S H
Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, Taiwan, Republic of China.
Nucl Med Commun. 1994 Nov;15(11):899-904. doi: 10.1097/00006231-199411000-00008.
The diagnostic efficacy of time-activity curves (TAC) and common bile duct dynamics (CBDD) derived from quantitative cholescintigraphy (QC) was assessed in patients with suspected sphincter of Oddi dysfunction (SOD). Quantitative cholescintigraphy was performed on 34 cholecystectomized individuals with suspected SOD and 26 asymptomatic controls. Each patient with suspected SOD underwent endoscopic retrograde cholangiography and sphincter of Oddi manometry (SOM). After exclusion of eight patients because of failure of manometry, the final diagnoses of the remaining 26 patients were taken as the gold standard by which to determine the detectability of TAC and CBDD. The sensitivity of TAC reached 68.8%. Common bile duct dynamics showed equal sensitivity but was more specific than TAC. The sensitivity improved to 87.5% when TAC and CBDD were combined. We conclude that non-invasive QC provides good sensitivity and specificity in evaluating cholecystectomized patients with suspected SOD.
在疑似Oddi括约肌功能障碍（SOD）的患者中，评估了定量胆系闪烁显像（QC）得出的时间-活性曲线（TAC）和胆总管动力学（CBDD）的诊断效能。对34例疑似SOD的胆囊切除患者和26例无症状对照者进行了定量胆系闪烁显像。每例疑似SOD患者均接受了内镜逆行胆管造影和Oddi括约肌测压（SOM）。因测压失败排除8例患者后，将其余26例患者的最终诊断作为确定TAC和CBDD可检测性的金标准。TAC的敏感性达到68.8%。胆总管动力学显示出相同的敏感性，但比TAC更具特异性。当TAC和CBDD联合使用时，敏感性提高到87.5%。我们得出结论，无创性QC在评估疑似SOD的胆囊切除患者时具有良好的敏感性和特异性。
