儿童期肾母细胞瘤后发生的十二指肠腺癌并伴有十二指肠结肠瘘

Beales I L, Scott H J

Department of Gastroenterology, Hammersmith Hospital, London, UK.

Postgrad Med J. 1994 Dec;70(830):933-6. doi: 10.1136/pgmj.70.830.933.

A case of a 44 year old man with a duodeno-colic fistula secondary to an adenocarcinoma of the second part of the duodenum is described. An asymptomatic leiomyoma of the second part of the duodenum was also present. The patient had been treated successfully for a right Wilms' cancer in childhood with surgery and radiotherapy. There are no previous reports of a duodenal carcinoma arising following a Wilms' tumour and cases of gastrointestinal adenocarcinoma arising as second malignancies following Wilms' tumours are reviewed. The aetiology of duodeno-colic fistulas is reviewed. Duodenal carcinoma is a unusual cause of duodeno-colic fistulas and this case may be unique in that respect.

本文描述了一例44岁男性患者，其因十二指肠第二部腺癌继发十二指肠结肠瘘。患者还存在十二指肠第二部无症状平滑肌瘤。该患者童年时曾因右肾母细胞瘤接受手术及放疗，治疗成功。此前尚无肾母细胞瘤后发生十二指肠癌的报道，本文对肾母细胞瘤后作为第二原发恶性肿瘤出现的胃肠道腺癌病例进行了综述。同时对十二指肠结肠瘘的病因进行了综述。十二指肠癌是十二指肠结肠瘘的罕见病因，就此而言，该病例可能具有独特性。