Marneros A, Rohde A, Deister A
Psychiatric University Hospital, Halle, Germany.
Psychopathology. 1995;28(1):32-7. doi: 10.1159/000284897.
Based on the phenomenological distinction of positive and negative symptoms, some authors discuss the existence of two subtypes of schizophrenia (positive vs. negative schizophrenia). Investigating the long-term course of 100 schizophrenic patients (on average 23 years after onset) it was found that only 24% of the patients had a stable monomorphous course (only once type of episode). The results of the presented longitudinal study do not support the assumption of 'purely positive' or 'purely negative' schizophrenic disorders. The relevance of positive and negative onset of illness for the long-term course and outcome is discussed with reference to the literature.
基于阳性和阴性症状的现象学区分，一些作者探讨了精神分裂症两种亚型（阳性型与阴性型精神分裂症）的存在。在对100例精神分裂症患者（平均起病后23年）的长期病程进行调查时发现，只有24%的患者病程稳定且单一（仅有一种发作类型）。所呈现的纵向研究结果并不支持“纯粹阳性”或“纯粹阴性”精神分裂症障碍的假设。本文结合文献讨论了疾病阳性和阴性起病对长期病程及预后的相关性。
