Gryglewski A, Pajdak W, Witkowski K
I Katedry Chirurgii Ogólnej, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 1994;51(7):303-7.
The presentation shows the survey of diseases the pathogenesis of which might be connected with the existence of Heat Shock Proteins (HSPs). We discuss the data referring to the influence of the HSPs upon the occurrence and progression of the following diseases: systemic lupus erythematosus, reactive arthritis, rheumatoid arthritis, insulin dependent diabetes mellitus, schizophrenia and Alzheimer's disease. There is also indicated a possible activity of HSPs in the pathogenesis of neoplasia, organ ischaemia and inflammation or degeneration.
该报告展示了对发病机制可能与热休克蛋白(HSPs)存在相关的疾病的调查。我们讨论了有关热休克蛋白对以下疾病的发生和发展影响的数据:系统性红斑狼疮、反应性关节炎、类风湿性关节炎、胰岛素依赖型糖尿病、精神分裂症和阿尔茨海默病。还指出了热休克蛋白在肿瘤形成、器官缺血以及炎症或变性的发病机制中可能具有的活性。