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[临床实践中从热带地区归来的旅行者]

[The traveler returning from the tropics in clinical practice].

作者信息

Markwalder K, Hatz C, Raeber P A

机构信息

Praxis für Tropenmedizin, Zürich.

出版信息

Schweiz Med Wochenschr. 1995 Feb 4;125(5):163-70.

PMID:7871399
Abstract

Travellers returning from the tropics frequently consult a physician even if they have no actual symptoms. Physical check-ups in asymptomatic returnees rarely detect dangerous conditions. The most common laboratory finding is intestinal parasites. Blood eosinophilia may indicate helminthic infections, such as strongyloidosis, filariasis, schistosomiasis and others. If there are no diagnostically suggestive symptoms a systematic, step-by-step workup is recommended (stool parasitology, serology, and special methods to demonstrate parasites in blood or tissues). The most common symptom of returnees from the tropics is diarrhea, or other disorders of intestinal motility. Appropriate investigations include parasitological and bacteriological tests, and--if the course is more chronic--endoscopy. If diarrhea is associated with fever, systemic infections (e.g. falciparum malaria) must be considered. Fever as a leading sign may mask a number of potentially dangerous infections. If there are no other obvious signs or symptoms indicating a particular etiology, the diagnostic approach should consider first of all those systemic infections, which are potentially life-threatening and can be cured by specific therapy, i.e. bacterial meningitis, falciparum malaria, septicemia (including typhoid fever), extraintestinal amebiasis, and African trypanosomiasis.

摘要

从热带地区归来的旅行者即使没有实际症状也常常会去看医生。对无症状归国者进行体格检查很少能发现危险病症。最常见的实验室检查结果是肠道寄生虫。血液嗜酸性粒细胞增多可能表明存在蠕虫感染,如类圆线虫病、丝虫病、血吸虫病等。如果没有具有诊断提示性的症状,建议进行系统的逐步检查(粪便寄生虫学检查、血清学检查以及在血液或组织中检测寄生虫的特殊方法)。从热带地区归来者最常见的症状是腹泻或其他肠道动力紊乱。适当的检查包括寄生虫学和细菌学检测,以及(如果病程较为慢性)内镜检查。如果腹泻伴有发热,必须考虑全身性感染(如恶性疟)。发热作为主要症状可能掩盖一些潜在的危险感染。如果没有其他明显迹象或症状表明特定病因,诊断方法首先应考虑那些可能危及生命且可通过特定疗法治愈的全身性感染,即细菌性脑膜炎、恶性疟、败血症(包括伤寒)、肠外阿米巴病和非洲锥虫病。

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