体外及人体中的持续性麻疹病毒感染
Persistent measles virus infection in vitro and in man.
作者信息
Viola M V, Scott C, Duffy P D
出版信息
Arthritis Rheum. 1978 Jun;21(5 Suppl):S47-51.
PMID:78715
Abstract
The characteristics of cell lines persistently infected with measles virus are described. Molecular mechanisms for measles virus-persistence in vitro as well as in human disease include defective interfering particles, mutant virus strains, proviral DNA, and nonpermissive cell types. The role of measles virus in subacute sclerosing panencephalitis and evidence for measles virus infection in multiple sclerosis, Paget's disease, and systemic lupus erythematosus are discussed.
摘要
本文描述了持续感染麻疹病毒的细胞系的特征。麻疹病毒在体外以及人类疾病中持续存在的分子机制包括缺陷干扰颗粒、突变病毒株、前病毒DNA和非允许细胞类型。文中讨论了麻疹病毒在亚急性硬化性全脑炎中的作用，以及在多发性硬化症、佩吉特病和系统性红斑狼疮中存在麻疹病毒感染的证据。
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