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成功运用单一化疗治疗获得性免疫缺陷综合征中伴有肠梗阻的广泛性胃肠道卡波西肉瘤。

Successful monochemotherapy of extensive gastrointestinal Kaposi's sarcoma with bowel obstruction in acquired immunodeficiency syndrome.

作者信息

Lingenfelser T, Daiss W, Overkamp D, Weber P

机构信息

Department of Medicine, Eberhard-Karls University Tübingen, Germany.

出版信息

Z Gastroenterol. 1994 Dec;32(12):688-90.

PMID:7871860
Abstract

We report the case history of a 28-year-old homosexual man of Caucasian origin whose diagnosis of acquired immunodeficiency syndrome was established one year before admission on the basis of a positive human immunodeficiency virus serology and cutaneous Kaposi's sarcoma. Severe postprandial vomiting pointed to bowel obstruction in an emaciated, poor risk patient. Endoscopy revealed multifocal, violaceous tumours throughout the upper gastrointestinal tract which, eventually, obstructed the duodenum. Histology confirmed the putative diagnosis of gastrointestinal Kaposi's sarcoma, which responded well to monochemotherapy with vincristine. Significant clinical improvement and repeat endoscopy indicated tumour regression and resolution of bowel obstruction.

摘要

我们报告了一名28岁的白种人同性恋男子的病史,其在入院前一年被诊断为获得性免疫缺陷综合征,诊断依据是人类免疫缺陷病毒血清学检测呈阳性以及患有皮肤卡波西肉瘤。严重的餐后呕吐表明一名消瘦、高危患者存在肠梗阻。内镜检查显示整个上消化道有多发性紫色肿瘤,最终阻塞了十二指肠。组织学检查证实了胃肠道卡波西肉瘤的推测诊断,该肿瘤对长春新碱单一化疗反应良好。显著的临床改善和重复内镜检查表明肿瘤消退且肠梗阻得到缓解。

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Successful monochemotherapy of extensive gastrointestinal Kaposi's sarcoma with bowel obstruction in acquired immunodeficiency syndrome.成功运用单一化疗治疗获得性免疫缺陷综合征中伴有肠梗阻的广泛性胃肠道卡波西肉瘤。
Z Gastroenterol. 1994 Dec;32(12):688-90.
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Kaposi'S sarcoma of the stomach and duodenum in human immunodeficiency virus infection.人类免疫缺陷病毒感染所致胃和十二指肠卡波西肉瘤。
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[Value of digestive endoscopic examination in acquired immunodeficiency syndrome (45 cases)].[消化内镜检查在获得性免疫缺陷综合征中的价值(45例)]
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引用本文的文献

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Predictive clinical factors in the diagnosis of gastrointestinal Kaposi's sarcoma and its endoscopic severity.预测胃肠道卡波西肉瘤的临床因素及其内镜严重程度。
PLoS One. 2012;7(11):e46967. doi: 10.1371/journal.pone.0046967. Epub 2012 Nov 30.