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吞咽障碍作为咽部肿瘤放疗的晚期后遗症。

Deglutition disorder as a late sequel of radiotherapy for a pharyngeal tumor.

作者信息

Dejaeger E, Goethals P

机构信息

Department of Internal Medicine, University Hospitals, Katholieke Universiteit Leuven, Belgium.

出版信息

Am J Gastroenterol. 1995 Mar;90(3):493-5.

PMID:7872294
Abstract

We present the case of a 62-yr-old patient who developed severe swallowing problems 5 yr after radiotherapy for a pharyngeal carcinoma. Although peripheral and cranial nerves are thought to be relatively radioresistant, cranial nerve damage can occur many years after radiotherapy. This may result in severe deglutition disorders and lead to a complete inability to eat normally. The aim is to demonstrate how these late sequelae can cause impairment of different structures involved in the swallowing process.

摘要

我们报告了一例62岁患者的病例,该患者在鼻咽癌放疗5年后出现严重吞咽问题。尽管外周神经和颅神经被认为对放疗相对耐受,但颅神经损伤可在放疗多年后发生。这可能导致严重的吞咽障碍,并导致完全无法正常进食。目的是展示这些晚期后遗症如何导致吞咽过程中涉及的不同结构受损。

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引用本文的文献

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Delayed lower cranial neuropathy after oropharyngeal intensity-modulated radiotherapy: A cohort analysis and literature review.口咽调强放疗后迟发性下颅神经病变:一项队列分析及文献综述
Head Neck. 2017 Aug;39(8):1516-1523. doi: 10.1002/hed.24789. Epub 2017 Apr 28.
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Dynamic Imaging Grade of Swallowing Toxicity (DIGEST): Scale development and validation.吞咽毒性动态成像分级(DIGEST):量表的开发与验证
Cancer. 2017 Jan 1;123(1):62-70. doi: 10.1002/cncr.30283. Epub 2016 Aug 26.
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How does radiotherapy impact swallowing function in nasopharynx and oropharynx cancer? Short-term results of a prospective study.
放射治疗如何影响鼻咽癌和口咽癌的吞咽功能?一项前瞻性研究的短期结果。
Acta Otorhinolaryngol Ital. 2016 Jun;36(3):174-84. doi: 10.14639/0392-100X-640. Epub 2016 Mar 31.
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Increased likelihood of long-term gastrostomy tube dependence in head and neck cancer survivors without partners.无伴侣的头颈部癌症幸存者长期依赖胃管的可能性增加。
Head Neck. 2013 Mar;35(3):420-5. doi: 10.1002/hed.22996. Epub 2012 Apr 14.