Schnapp K A, Platz M S
Department of Chemistry, Ohio State University, Columbus 43210.
Bioconjug Chem. 1993 Mar-Apr;4(2):178-83. doi: 10.1021/bc00020a011.
Several fluorinated aryl azides (2,6 and 2,4-difluorophenyl azide, 2,4,6-triflurorophenyl azide, and methyl 4-azido-2,3,5,6-tetrafluorobenzoate) were studied by laser flash photolysis techniques. In each case, the azides from singlet nitrenes which can be intercepted with pyridine to form ylides. This allowed determination of the rate constant for ring expansion of the singlet nitrene to the dehydroazepine and measurement of the absolute rate constants for reaction of the singlet nitrenes with typical quenchers.
通过激光闪光光解技术研究了几种氟化芳基叠氮化物（2,6 - 二氟苯基叠氮化物、2,4 - 二氟苯基叠氮化物、2,4,6 - 三氟苯基叠氮化物和4 - 叠氮基 - 2,3,5,6 - 四氟苯甲酸甲酯）。在每种情况下，叠氮化物会生成单线态氮烯，该单线态氮烯可与吡啶发生截获反应形成叶立德。这使得能够确定单线态氮烯环化生成脱氢氮杂卓的速率常数，并测量单线态氮烯与典型猝灭剂反应的绝对速率常数。
