Orphanides G, Maxwell A
Department of Biochemistry, University of Leicester, UK.
Curr Biol. 1994 Nov 1;4(11):1006-9. doi: 10.1016/s0960-9822(00)00227-x.
The ability of type II DNA topoisomerases to pass one DNA double helix through another can be explained by a mechanism involving two gates in the enzyme structure.
II型DNA拓扑异构酶使一条DNA双螺旋穿过另一条的能力,可以用一种涉及酶结构中两个门控的机制来解释。