Lofaso F, Heyer L, Leroy A, Lorino H, Harf A, Isabey D
Service de Physiologie-Explorations Fonctionnelles, Hôpital Henri Mondor, Créteil, France.
Eur Respir J. 1994 Nov;7(11):2077-81.
Nasal continuous positive airway pressure (CPAP) devices with a servo-mechanism to control pressure have recently been developed. We evaluated six such devices and three conventional systems in terms of effectiveness in maintaining constant pressure. Machines were tested with pressure levels of 5, 10 and 15 cmH2O. Dynamic behaviour was evaluated: 1) by calculating the imposed work of breathing during simulated breath generated by a sinusoidal pump; and 2) by following the fall in pressure after a transient flow of 1 l.s-1. Quasi-static behaviour was evaluated by simulating a predetermined air leak. Under dynamic conditions, work of breathing was lowest with one conventional nasal CPAP device and three servo-controlled nasal CPAP devices; whereas, the highest levels of work of breathing were recorded with two servo-controlled nasal CPAP devices. The pressure-time response to a transient flow yielded similar results, with a significant inverse correlation between pressure values observed after 300 ms and imposed work of breathing during simulated breathing (r = -0.91). Under quasi-static conditions, microprocessor servo-controlled devices exhibited the best performance. These results suggest that microprocessor servo-controlled nasal CPAP devices are not always the best systems for maintaining constant airway pressure in dynamic situations. However, they are more effective in ensuring maintenance of the desired pressure in the event of an air leak at the mask.
最近开发出了带有伺服机制以控制压力的鼻持续气道正压通气(CPAP)设备。我们就维持恒定压力的有效性对6种此类设备和3种传统系统进行了评估。在5、10和15厘米水柱的压力水平下对这些机器进行了测试。对动态行为进行了评估:1)通过计算正弦泵产生的模拟呼吸过程中施加的呼吸功;2)通过跟踪1升·秒⁻¹的瞬态气流后压力的下降情况。通过模拟预定的空气泄漏来评估准静态行为。在动态条件下,一种传统鼻CPAP设备和三种伺服控制鼻CPAP设备的呼吸功最低;而两种伺服控制鼻CPAP设备的呼吸功水平最高。对瞬态气流的压力 - 时间响应产生了类似的结果,在300毫秒后观察到的压力值与模拟呼吸过程中施加的呼吸功之间存在显著的负相关(r = -0.91)。在准静态条件下,微处理器伺服控制设备表现出最佳性能。这些结果表明,微处理器伺服控制的鼻CPAP设备在动态情况下并不总是维持恒定气道压力的最佳系统。然而,在面罩出现空气泄漏的情况下,它们在确保维持所需压力方面更有效。