Gupta K G, Loya Y S, Sharma S
Department of Cardiology, BYL Nair Hospital, Bombay.
Indian Heart J. 1994 Jul-Aug;46(4):157-60.
Twenty patients with discrete subaortic stenosis were studied during last 11 years. Cross sectional echocardiography and angiography demonstrated a membrane in 17 (85%), fibromuscullar collar in 2 (10%), and diffuse tunnel type of obstruction in 1 (5%) patient. Eighty five percent of patients had severe obstruction with average peak systolic gradients being 96.5 +/- 36.3 mm of Hg. Eight patients with membranous obstruction seen during the last 5 years underwent successful balloon dilatation with decrease in peak systolic gradient from 107.1 +/- 24.2 to 32.3 +/- 14.2. The haemodynamic benefits were sustained during 4 to 24 (mean 9.6) months followup. The results indicate that balloon dilatation can be a safe and effective treatment for thin subaortic membrane. Surgical resection is needed in patients with collar or tunnel type of obstruction.
在过去11年中对20例孤立性主动脉瓣下狭窄患者进行了研究。横断面超声心动图和血管造影显示,17例(85%)有隔膜,2例(10%)有纤维肌性环,1例(5%)有弥漫性隧道型梗阻。85%的患者有严重梗阻,平均收缩期峰值压差为96.5±36.3 mmHg。在过去5年中见到的8例膜性梗阻患者成功接受了球囊扩张术,收缩期峰值压差从107.1±24.2降至32.3±14.2。在4至24个月(平均9.6个月)的随访中,血流动力学益处得以维持。结果表明,球囊扩张术对于薄的主动脉瓣下隔膜可能是一种安全有效的治疗方法。对于有环或隧道型梗阻的患者需要进行手术切除。