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[肠道药物转运:一个外科问题?]

[Intestinal drug transport: a surgical problem?].

作者信息

John H, Renner N, Schönenberger R, Harder F

机构信息

Departement Chirurgie, Universitätskliniken des Kantonsspitals Basel.

出版信息

Helv Chir Acta. 1994 Dec;60(6):935-8.

PMID:7876014
Abstract

The case of a 35-year-old man is reported, who presented himself in the emergency room with anxiety and hallucinations. He then passed a small oval pack consisting of a dark paste wrapped in cellophane with his stool. This led to the suspicion of a "body packer syndrome" with cocaine intoxication. The plain abdominal X-ray revealed multiple oval structure scattered over the entire gastrointestinal tract. Cocaine metabolites in the urine confirmed the diagnosis. During the following whole-bowel irrigation the patient had a grand mal seizure. In order to accelerate the retrieval of this threatening load, surgical evacuation was immediately executed. 78 packs containing 650 grams cocaine were removed through a gastrotomy and a coecotomy, respectively. Two of these packs were leaking. Following an uneventful postoperative course the patient was discharged from the hospital 11 days later. According to the literature the recommended treatment for cocaine body packers is whole bowel irrigation. Operative treatment is mandatory in cases of small bowel obstruction or drug intoxication due to leaking packs.

摘要

报告了一名35岁男性的病例,他因焦虑和幻觉前往急诊室就诊。随后他随粪便排出了一个小的椭圆形包裹,包裹由玻璃纸包裹着深色糊状物组成。这引发了对“人体藏毒综合征”伴可卡因中毒的怀疑。腹部平片显示整个胃肠道散在多个椭圆形结构。尿液中的可卡因代谢物证实了诊断。在随后的全肠道灌洗过程中,患者发生了癫痫大发作。为了加速取出这种有威胁的包裹,立即进行了手术清除。通过胃切开术和盲肠切开术分别取出了78个装有650克可卡因的包裹。其中两个包裹有渗漏。术后过程顺利,患者于11天后出院。根据文献,对于可卡因人体藏毒者推荐的治疗方法是全肠道灌洗。对于小肠梗阻或因包裹渗漏导致药物中毒的情况,手术治疗是必需的。

相似文献

1
[Intestinal drug transport: a surgical problem?].[肠道药物转运:一个外科问题?]
Helv Chir Acta. 1994 Dec;60(6):935-8.
2
[Cocaine poisoning from transport of the drug in the gastrointestinal tract (the body-packer syndrome)].[因药物在胃肠道运输导致的可卡因中毒(人体包装者综合征)]
Dtsch Med Wochenschr. 1992 Dec 22;117(51-52):1952-5. doi: 10.1055/s-2008-1062535.
3
[Cocaine-body-packing. Infrequent indication for laparotomy].[可卡因体内藏毒。剖腹手术的罕见指征]
Chirurg. 2003 Jul;74(7):626-31. doi: 10.1007/s00104-002-0603-5.
4
Conservative management of cocaine-packet ingestion: experience in Milan, the main Italian smuggling center of South American cocaine.可卡因包裹摄入的保守治疗:在意大利主要的南美可卡因走私中心米兰的经验。
Panminerva Med. 1996 Jun;38(2):111-6.
5
[Diagnosis and treatment of 'body packer' syndrome].["人体藏毒者综合征的诊断与治疗"]
Ned Tijdschr Geneeskd. 2007 Aug 25;151(34):1868-73.
6
[Intestinal occlusion in cocaine-packet ingestion].
Minerva Chir. 1993 Oct 31;48(20):1233-7.
7
[Atypical "body packing syndrome"--a case report].
Arch Kriminol. 2006 Jul-Aug;218(1-2):35-43.
8
['Body-packer' syndrome: an important disease with forensic-medical aspects].“人体藏毒者”综合征:一种具有法医学意义的重要疾病
Ned Tijdschr Geneeskd. 2003 May 31;147(22):1041-5.
9
The risk of body packing: a case of a fatal cocaine overdose.人体藏毒的风险:一例致命的可卡因过量案例
Forensic Sci Int. 2005 Jun 30;151(1):81-4. doi: 10.1016/j.forsciint.2004.07.005.
10
The cocaine 'body packer' syndrome. Diagnosis and treatment.可卡因“人体携毒者”综合征。诊断与治疗。
JAMA. 1983 Sep 16;250(11):1417-20.

引用本文的文献

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Surgical treatment in cocaine body packers and body pushers.可卡因体内藏毒者和运毒者的外科治疗
Int J Colorectal Dis. 2007 Dec;22(12):1531-5. doi: 10.1007/s00384-007-0324-9. Epub 2007 May 23.