Ehrich W
Klin Monbl Augenheilkd. 1976 Apr;168(4):493-501.
For six months the anterior chambers of rabbits were examined at regular intervals with the slit-lamp photograph. The reactions of iris, aqueous, and cornea were observed after implanting one PMMA-disc (0.25 mm thickness and 1.5 mm diameter) through a lancet incision. At the place where the disc touched the iris one could see during the half year period hyperaemia iridis, ciliary injection, atrophia iridis, and foreign-substance-granuloma of the iris with partial adhesion of the iris wrinkles. The cause for these reactions is a toxin in the PMMA. Mechanical irritation and plastic alteration could be excluded by the experimental method.
连续六个月定期用裂隙灯照相检查兔的前房。通过刺切口植入一片PMMA盘(厚度0.25mm,直径1.5mm)后,观察虹膜、房水和角膜的反应。在半年期间,可以看到在盘接触虹膜的部位出现虹膜充血、睫状充血、虹膜萎缩以及虹膜异物肉芽肿伴虹膜皱襞部分粘连。这些反应的原因是PMMA中的一种毒素。通过实验方法可以排除机械刺激和塑性改变。