Schmitt H
Klin Monbl Augenheilkd. 1976 Apr;168(4):518-26.
After intralamellar implantation of Teflon-membranes (4,0 mm/0,125 mm) without perforation there is an epithelial thinning over the membrane after 6 days, after 15 days metachromatical staining over the membrane is reduced, after 21 days there is a central defect of the cornea over the membrane and after 28 days the membrane is pushed out of the cornea. When Teflon-membranes (4,0 mm/0,125 mm) are inserted with one central perforation or three perforations of 1 mm epithelial thinning, reduced metachromasia and defects of the cornea over the membrane occurred later. But even these membranes are pushed out of the cornea after some time. The results with thinner Teflon-membranes (4.0 mm/0.05 mm) do not show much difference. The reason for the reduced metachromasia of the cornea over Teflon-membranes seems to be a lower rate of syntheses of glycosaminoglycanes because of the reduced glucose content in this part of the cornea. As the experiments with the intracorneal control-pockets without implantation of a Teflon-membrane show, wound-healing is not responsible for the reduced metachromasia over the membrane.
在层间植入未穿孔的聚四氟乙烯膜（4.0毫米/0.125毫米）后，6天后膜上方出现上皮变薄，15天后膜上的异染性染色减少，21天后膜上方角膜出现中央缺损，28天后膜被推出角膜。当插入带有一个中央穿孔或三个1毫米穿孔的聚四氟乙烯膜（4.0毫米/0.125毫米）时，上皮变薄、异染性降低和膜上方角膜缺损出现得较晚。但即使是这些膜在一段时间后也会被推出角膜。较薄的聚四氟乙烯膜（4.0毫米/0.05毫米）的结果没有太大差异。聚四氟乙烯膜上方角膜异染性降低的原因似乎是由于角膜该部分葡萄糖含量降低，糖胺聚糖的合成速率较低。正如未植入聚四氟乙烯膜的角膜内对照袋实验所示，伤口愈合不是膜上异染性降低的原因。
