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[通过单能X线吸收法测量跟骨骨矿物质]

[Bone mineral measurement of the calcaneus by single X-ray absorptiometry].

作者信息

Katagiri H

机构信息

Department of Orthopedic Surgery, Faculty of Medicine, Tottori University, Japan.

出版信息

Nihon Seikeigeka Gakkai Zasshi. 1994 Dec;68(12):1044-55.

PMID:7876684
Abstract

The bone mineral content (BMC) of the calcaneus was evaluated using single X-ray absorptiometry (SXA) with respect to reproducibility of bone mineral measurement, age-related bone loss in healthy Japanese, the spine fracture threshold in osteoporotic women, and the effect of non-weight bearing on bone mass in patients after hip arthroplasty. The mean reproducibilities using this method in vitro and in vivo were 0.81% and 0.59%. In 264 healthy men aged between 21 and 79 years and 328 healthy women aged between 20 and 79 years, the calcaneus BMC reached a peak in their twenties and thereafter decreased linearly with age by 0.57% per year in men and 1.32% per year in women. Body height and weight were well correlated with the calcaneus BMC in healthy men and women (p < 0.001). The bone mineral density (BMD) of the lumbar spine was measured using dual X-ray absorptiometry (DXA) and was significantly correlated with the calcaneus BMC in both men (r = 0.727, p < 0.001) and women (r = 0.703, p < 0.001). The fracture threshold, defined as the 90th percentile for calcaneus BMC in a woman with a vertebral fracture, was 313.31 mg/cm2 and 70.2% of the peak bone mass in the calcaneus. In 30 patients with hip implant arthroplasty, the bone mass in the calcaneus, lumbar spine and the distal radius was evaluated longitudinally during a follow-up period of one year. Only the calcaneus BMC in the treated leg changed significantly during this period. In the first four months, the calcaneus BMC in the treated leg diminished by approximately 21%, but had recovered by one year after surgery. We concluded that bone mineral measurement in the calcaneus was useful for evaluating age-related bone mass changes in healthy men and women, bone loss in osteoporotic patients, and the effect of non-weight bearing on bone mass in patients after hip arthroplasty.

摘要

使用单能X线吸收法(SXA)评估跟骨的骨矿物质含量(BMC),内容涉及骨矿物质测量的可重复性、健康日本人的年龄相关性骨质流失、骨质疏松女性的脊柱骨折阈值以及髋关节置换术后患者非负重对骨量的影响。该方法在体外和体内的平均可重复性分别为0.81%和0.59%。在264名年龄在21至79岁之间的健康男性和328名年龄在20至79岁之间的健康女性中,跟骨BMC在二十多岁时达到峰值,此后随年龄线性下降,男性每年下降0.57%,女性每年下降1.32%。健康男性和女性的身高和体重与跟骨BMC密切相关(p < 0.001)。使用双能X线吸收法(DXA)测量腰椎的骨矿物质密度(BMD),其与男性(r = 0.727,p < 0.001)和女性(r = 0.703,p < 0.001)的跟骨BMC均显著相关。骨折阈值定义为椎体骨折女性跟骨BMC的第90百分位数,为313.31 mg/cm²,是跟骨峰值骨量的70.2%。在30例髋关节置换术患者中,在一年的随访期内纵向评估跟骨、腰椎和桡骨远端的骨量。在此期间,仅患侧跟骨BMC发生显著变化。在最初四个月,患侧跟骨BMC减少了约21%,但术后一年恢复。我们得出结论,跟骨的骨矿物质测量有助于评估健康男性和女性的年龄相关性骨量变化、骨质疏松患者的骨质流失以及髋关节置换术后患者非负重对骨量的影响。

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