Yoshida J, Nagai K, Hasebe T, Takahashi K, Nishimura M, Otsuka S, Nishiwaki Y, Kodama T
Department of Thoracic Diseases, National Cancer Center Hospital East, Chiba.
Jpn J Clin Oncol. 1995 Feb;25(1):20-4.
A 50-year-old man underwent a left nephrectomy for renal cell carcinoma of the clear cell type in February, 1978. He was examined using computed tomography in September, 1993, and was found to have a small coin lesion in his right lung. A fine needle aspiration biopsy failed to disclose any tumor cells. He underwent a video-assisted thoracoscopic biopsy of the right lung in February, 1994, 16 years after his nephrectomy. The resected specimen contained a coin lesion measuring approximately 1 cm in diameter, and the lesion was microscopically diagnosed as a renal cell carcinoma of the clear cell type metastatic to the lung. The patient is doing well with no signs of re-recurrence six months after the resection of the metastatic lesion. To our knowledge, the time interval between his nephrectomy and resection of the metastatic lesion is the longest ever reported in Japan.
一名50岁男性于1978年2月因透明细胞型肾细胞癌接受了左肾切除术。1993年9月，他接受了计算机断层扫描检查，发现右肺有一个小的硬币状病变。细针穿刺活检未发现任何肿瘤细胞。1994年2月，在他肾切除术后16年，他接受了右肺电视辅助胸腔镜活检。切除的标本中有一个直径约1厘米的硬币状病变，显微镜检查诊断为转移至肺部的透明细胞型肾细胞癌。在切除转移病变六个月后，患者情况良好，没有复发迹象。据我们所知，他肾切除与转移病变切除之间的时间间隔是日本有报道以来最长的。
