细胞周期蛋白依赖性激酶（CDK）调控原理。
Principles of CDK regulation.
作者信息
Morgan D O
机构信息
Department of Physiology, University of California, San Francisco 94143-0444.
出版信息
Nature. 1995 Mar 9;374(6518):131-4. doi: 10.1038/374131a0.
DOI:10.1038/374131a0
PMID:7877684
Abstract
As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.
摘要
作为细胞周期的关键调节因子，细胞周期蛋白依赖性激酶必须受到细胞外和细胞内信号的严格调控。细胞周期蛋白依赖性激酶的活性受四种高度保守的生化机制控制，形成了一个优雅复杂程度无与伦比的调控途径网络。
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