Jansen B P, Pasteuning W H, Schellens R L, Tijssen C C
Afd. Neurologie, St. Elisabeth Ziekenhuis, Tilburg.
Ned Tijdschr Geneeskd. 1995 Feb 18;139(7):338-41.
In four patients, 2 women aged 24 and 35 and 2 men aged 37 and 47 years, an ischaemic stroke was observed and an atrial septal aneurysm was found as a possible cardiac source of embolism to the brain. Atrial septal aneurysm is a bulging of the fossa ovalis region, that can be visualised by (preferably transoesophageal) echocardiography. In the four patients there were only few other risk factors for ischaemic stroke (migraine, smoking, oral contraceptives). Cerebral angiography was normal in all cases. Recent literature suggests that a causal relationship exists between atrial septal aneurysm and ischaemic stroke. It is still uncertain what treatment is best.
在4例患者中，2名女性分别为24岁和35岁，2名男性分别为37岁和47岁，均发生了缺血性卒中，并发现房间隔瘤可能是脑栓塞的心脏来源。房间隔瘤是卵圆窝区域的膨出，可通过（最好是经食管）超声心动图显示。在这4例患者中，缺血性卒中的其他危险因素很少（偏头痛、吸烟、口服避孕药）。所有病例的脑血管造影均正常。近期文献表明，房间隔瘤与缺血性卒中之间存在因果关系。目前仍不确定哪种治疗方法最佳。
