Olgaard K, Heerfordt J, Madsen S
Nephron. 1976;17(5):325-34. doi: 10.1159/000180738.
99Tcm-polyphosphate (Tc-PP) bone scintigraphy was performed in 30 consecutive uremic patients on regular hemodialysis and compared with a normal control group. 27 of the patients (90%) had pathological accumulation on the scintigrams, while roentgenographic abnormalities were present in only 10 patients (33%), indicating that scintigraphy is superior to X-ray in the early detection of skeletal changes in uremic patients. In the group with the most pronounced uptake on the scintigrams there was a preponderance of previously kidney-transplanted patients, while no correlation could be demonstrated between the severity of the scintigraphic findings and the duration of the hemodialysis period, the anephric state of the patients, the underlying kidney disease or the sex. It is suggested that intensive glucocorticoid treatment, even of short duration in the previously kidney-transplanted patients, may aggravate uremic osteodystrophy.
对30例接受定期血液透析的尿毒症患者进行了99锝-多聚磷酸盐（Tc-PP）骨闪烁显像检查，并与正常对照组进行比较。27例患者（90%）的闪烁显像图上有病理聚集，而X线片异常仅见于10例患者（33%），这表明在尿毒症患者骨骼变化的早期检测中，闪烁显像优于X线检查。在闪烁显像图上摄取最为明显的患者组中，既往接受过肾移植的患者占多数，而闪烁显像结果的严重程度与血液透析时间、患者的无肾状态、潜在的肾脏疾病或性别之间均未显示出相关性。提示即使是对既往接受过肾移植的患者进行短期的强化糖皮质激素治疗，也可能会加重尿毒症骨营养不良。
