[天然免疫调节剂对百日咳菌苗引起的继发性免疫缺陷的纠正作用模式]
[The patterns of the corrective action of a natural immunomodulator on the secondary immunological defect caused by a corpuscular pertussis vaccine].
作者信息
Semenova I B, Akatov A K
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1994 Sep-Oct(5):57-9.
PMID:7879484
Abstract
Purified staphylococcal toxoid (PST) was shown to be capable of preventing the development of secondary antigen-nonspecific immune deficiency in mice, immunized with whole-cell pertussis vaccine. The immunocorrective action of PST was manifested after its injection before (on day -1), simultaneously with and after (on day +1) the injection of whole-cell pertussis vaccine. Correction was either complete or partial, depending on the scheme of the experiment and the dose of PST.
摘要
纯化葡萄球菌类毒素（PST）已被证明能够预防用全细胞百日咳疫苗免疫的小鼠继发抗原非特异性免疫缺陷的发生。PST的免疫纠正作用在其于注射全细胞百日咳疫苗之前（第-1天）、同时以及之后（第+1天）注射后均有体现。根据实验方案和PST剂量的不同，纠正作用可以是完全的或部分的。
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