Hirabayashi Y, Shimizu R, Saitoh K, Fukuda H
Department of Anaesthesiology, Jichi Medical School, Tochigi, Japan.
Br J Anaesth. 1995 Jan;74(1):41-5. doi: 10.1093/bja/74.1.41.
We have compared the spread of subarachnoid hyperbaric amethocaine in adolescents with that in adults. Amethocaine 8 mg in 2 ml of 10% glucose was injected through a 25-gauge spinal needle inserted at the L3-4 interspace in 21 adolescents aged 12-16 yr and in 111 adults aged 17-82 yr. Although we found no differences in height, weight or body mass index between the adolescents and adults, maximum spread of analgesia was significantly higher in the adolescents (median T3 (range T4-C5) than in the adults (T4 (T9-C7)). We conclude that subarachnoid injection of hyperbaric amethocaine produces an unexpectedly higher level of analgesia in adolescents than in adults.
我们比较了青少年与成人蛛网膜下腔注射高比重丁卡因的扩散情况。将8毫克丁卡因溶于2毫升10%葡萄糖溶液中,通过25G腰穿针于L3 - 4椎间隙注入21名12 - 16岁青少年和111名17 - 82岁成人。虽然我们发现青少年与成人在身高、体重或体重指数方面无差异,但青少年镇痛的最大扩散范围(中位数T3(范围T4 - C5))显著高于成人(T4(T9 - C7))。我们得出结论,蛛网膜下腔注射高比重丁卡因在青少年中产生的镇痛水平比成人中意外地更高。