Kluge R, Meyer J, Rapp K G
Institut für Versuchstierkunde der RWTH Aachen.
J Exp Anim Sci. 1994 Nov;36(6):179-88.
A total of 15 strains of mice (11 inbred lines, 4 outbred stocks) of the institute for animal breeding of the veterinary faculty of the university of Munich (FRG) were scored for 23 biochemical loci each. The allelic distribution and frequencies were recorded as a basis for a so far not established genetic monitoring system. The inbred strains revealed the expected homozygosity with one exception (strain UMDH/+; locus Es1). The outbred stocks showed a remarkable degree of variable loci (17.4-36.3%) with a mean heterozygosity between 0.05 and 0.12. The markers in use allow differentiation between all strains (except for one pair of sublines) and stocks. 14 of the loci show allelic differences among the strains and thus can be used for a genetic monitoring system.
慕尼黑大学（联邦德国）兽医学院动物育种研究所的总共15个品系的小鼠（11个近交系，4个远交群），每个品系针对23个生化位点进行了评分。记录了等位基因分布和频率，作为迄今尚未建立的遗传监测系统的基础。除了一个例外（UMDH/+品系；Es1位点），近交系显示出预期的纯合性。远交群显示出相当程度的可变位点（17.4 - 36.3%），平均杂合度在0.05至0.12之间。所使用的标记能够区分所有品系（除了一对亚系）和远交群。其中14个位点在品系间显示出等位基因差异，因此可用于遗传监测系统。
