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颗粒大小和化学成分对清除机制效率的影响:人体电子显微镜研究

Influence of particle size and chemical composition on efficiency of clearance mechanisms: electron microscopy studies on humans.

作者信息

Falchi M, Donelli G, Paoletti L

机构信息

Department of Ultrastructures, Istituto Superiore di Sanita, Rome, Italy.

出版信息

Environ Health Perspect. 1994 Oct;102 Suppl 5(Suppl 5):241-3. doi: 10.1289/ehp.94102s5241.

Abstract

This article compares the presence of solid particles in lung parenchyma samples collected from accident victims and in bronchoalveolar lavage fluid taken from patients diagnosed with pulmonary carcinoma. Analysis by electron microscopy showed differences in particle size between the two groups, which could be attributable both to differences in original particle size and to their solubility in the biological environment.

摘要

本文比较了从事故受害者采集的肺实质样本以及从被诊断患有肺癌的患者获取的支气管肺泡灌洗 fluid 中的固体颗粒情况。电子显微镜分析显示两组之间颗粒大小存在差异,这可能既归因于原始颗粒大小的差异,也归因于它们在生物环境中的溶解度。

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