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[间歇性自主通气。慢性呼吸泵疲劳的治疗]

[Intermittent self-ventilation. Therapy of chronic respiratory pump fatigue].

作者信息

Schönhofer B, Köhler D

机构信息

Krankenhaus Kloster Grafschaft.

出版信息

Fortschr Med. 1995 Jan 20;113(1-2):46-8.

PMID:7883266
Abstract

Chronic fatigue of the respiratory pump may be due either to constant overexertion of otherwise healthy muscles of respiration (e.g. due to chronic obstructive lung disease, scoliosis) or to certain neuromuscular diseases (e.g. Duchenne type muscular dystrophy). Intermittent self-ventilation (ISV) is employed--in particular at night--in order to prevent imminent exhaustion of the respiratory muscles. The relief provided by ISV gives the muscles a chance to recover. The muscles of respiration can be largely rested by the use of volume-controlled ventilation (IPPV), or partially rested by-BiPAP ventilation (Stimotron). Two main approaches to ventilation are available: non-invasive via a breathing mask or, if this is not possible, invasive ventilation via a tracheostomy. In addition to the commercially available standard nasal masks, we more often make use of custom-made so-called Grafschaft nose-and-mouth masks. The early provision of support for the muscles of respiration can obviate, or at least delay, the need for emergency intubation and subsequent assisted ventilation in an icu in endangered patients.

摘要

呼吸泵的慢性疲劳可能是由于原本健康的呼吸肌持续过度劳累(例如由于慢性阻塞性肺疾病、脊柱侧弯),或者是由于某些神经肌肉疾病(例如杜兴氏型肌营养不良症)。采用间歇性自主通气(ISV)——尤其是在夜间——以防止呼吸肌即将出现的疲劳。ISV提供的缓解使肌肉有机会恢复。通过使用容量控制通气(IPPV),呼吸肌可在很大程度上得到休息,或者通过双水平气道正压通气(BiPAP通气,即刺激通气)部分得到休息。有两种主要的通气方法:通过呼吸面罩进行无创通气,或者在无法做到这一点时,通过气管切开术进行有创通气。除了市售的标准鼻罩外,我们更常使用定制的所谓格拉夫schaft口鼻面罩。尽早为呼吸肌提供支持可以避免,或者至少延迟濒危患者在重症监护病房进行紧急插管和随后的辅助通气的必要性。

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