Koo J Y, Shellow W V, Hallman C P, Edwards J E
Department of Dermatology, University of California at San Francisco Medical Center.
Int J Dermatol. 1994 Dec;33(12):849-50. doi: 10.1111/j.1365-4362.1994.tb01018.x.
The relationship between psychiatric disorders and alopecia areata has not been well studied. Although previous reports have been unable to correlate psychiatric illness with hair loss, a recent study determined that 74% of patients with alopecia areata (AA) under evaluation had one or more lifetime psychiatric diagnoses.
Two hundred and ninety-four community-based patients with alopecia areata responded to a detailed questionnaire distributed by Help Alopecia International Research, Inc. The prevalence of psychiatric disorders was determined using diagnostic criteria from the Diagnostic and Statistical Manual of Mental Disorders (DSM-IIIR).
Major depression, generalized anxiety disorder, social phobia, and paranoid disorder were all present in patients with alopecia areata at rates significantly higher than in the general population.
Alopecia areata patients are at a higher risk of developing psychiatric comorbidity during their clinical course.
精神疾病与斑秃之间的关系尚未得到充分研究。尽管先前的报告未能将精神疾病与脱发联系起来，但最近的一项研究确定，接受评估的斑秃（AA）患者中有74%在一生中被诊断出患有一种或多种精神疾病。
294名社区斑秃患者对国际脱发援助研究公司分发的一份详细问卷做出了回应。使用《精神疾病诊断与统计手册》（DSM-IIIR）的诊断标准确定精神疾病的患病率。
斑秃患者中重度抑郁症、广泛性焦虑症、社交恐惧症和偏执性障碍的发生率均显著高于普通人群。
斑秃患者在其临床病程中发生精神疾病共病的风险更高。
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