Colón E A, Popkin M K, Callies A L, Dessert N J, Hordinsky M K
Department of Psychiatry, University of Minnesota, Minneapolis.
Compr Psychiatry. 1991 May-Jun;32(3):245-51. doi: 10.1016/0010-440x(91)90045-e.
Thirty-one patients with alopecia areata were administered a structured psychiatric interview (the Diagnostic Interview Schedule; DIS). Overall, 74% had one or more lifetime psychiatric diagnoses. Particularly noteworthy were the high lifetime prevalence rates of major depression (39%) and generalized anxiety disorder (39%). In addition, patients reported increased rates of psychiatric disorders in first-degree relatives: anxiety disorders (58%), affective disorders (35%), and substance use disorders (35%). Patients with patchy alopecia areata were more likely to have a diagnosis of generalized anxiety disorder. No relationships were found between major depression and any variable characterizing alopecia areata history. Possible interrelationships between psychiatric disorders and alopecia areata are discussed. The study suggests that patients with alopecia areata are at increased risk for psychiatric disorders, and calls attention to the need for psychiatric assessment in this population.
对31名斑秃患者进行了结构化精神科访谈（诊断性访谈表；DIS）。总体而言，74%的患者有一项或多项终生精神疾病诊断。特别值得注意的是重度抑郁症（39%）和广泛性焦虑症（39%）的终生患病率较高。此外，患者报告一级亲属中精神疾病的发病率增加：焦虑症（58%）、情感障碍（35%）和物质使用障碍（35%）。斑秃斑片状患者更有可能被诊断为广泛性焦虑症。未发现重度抑郁症与斑秃病史的任何特征变量之间存在关联。讨论了精神疾病与斑秃之间可能的相互关系。该研究表明斑秃患者患精神疾病的风险增加，并提请注意对该人群进行精神科评估的必要性。
