Passl R, Eibl M, Egkher E, Frisee H, Gaudernak T, Neugebauer G, Vécsei W
Wien Klin Wochenschr. 1976 Oct 1;88(78):585-8.
This study was undertaken in order to assess the clinical and immunological consequences of splenectomy for traumatic reasons in childhood. Immunological testing of 22 persons 1 to 20 years subsequent to removal of the spleen for traumatic rupture between the ages of 3 and 6 revealed diminished or absent agglutinins in 10 cases and diminished or absent opsonins to E. coli in 16 cases. All patients were in good health and no clinical evidence of increased susceptibility to severe infections was found postoperatively. It is, therefore, assumed that the diagnosed defects had been compensated for by other immunological mechanisms. In contrast to the opinions of other authors, it is concluded that splenectomy in childhood between the ages of 3 and 6 does not appear to carry greater risks than in later years.
本研究旨在评估儿童期因外伤行脾切除术后的临床和免疫后果。对22例3至6岁因外伤性脾破裂而切除脾脏的患者在术后1至20年进行免疫检测,结果显示10例患者凝集素减少或缺失,16例患者对大肠杆菌的调理素减少或缺失。所有患者健康状况良好,术后未发现对严重感染易感性增加的临床证据。因此,推测所诊断出的缺陷已由其他免疫机制代偿。与其他作者的观点相反,得出的结论是,3至6岁儿童期行脾切除术似乎并不比 later years 有更大风险。 (注:原文中“later years”表述不太准确,可能是想表达“以后的年龄段”之类的意思,但按要求保留原文翻译。)