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[出生后第6个月出现的常染色体显性遗传性癫痫,预后良好]

[Autosomal dominant cerebral seizures in the 6th month of life with benign outcome].

作者信息

Kurlemann G, Vossschulte P, Weglage J, Palm D G

机构信息

Universitäts-Kinderklinik, Bereich Neuropädiatrie, Münster.

出版信息

Klin Padiatr. 1995 Jan-Feb;207(1):17-8. doi: 10.1055/s-2008-1046502.

Abstract

We report a boy with benign familial seizures of the sixth month of life. At the age of six months he suffered his first afebrile grand mal seizure. Up to his ninth month several seizures of the same type occurred. EEGs were always normal. The history yielded a paternal hereditary trait: five members of the family had also suffered grand mal seizures in the sixth month of life. All but one had no therapy with antiepileptic drugs. One girl was treated with phenobarbital for two years. All members of the family show normal neurological development. Under low dose therapy with phenobarbital our patient has remained seizure-free up to now.

摘要

我们报告了一名患有良性家族性癫痫的男婴,发病于6个月大时。6个月大时,他首次出现无热惊厥大发作。到9个月大时,又发生了几次相同类型的惊厥。脑电图检查始终正常。家族史显示存在父系遗传特征:家族中有5名成员在6个月大时也曾发生惊厥大发作。除1人外,其他人都未接受抗癫痫药物治疗。一名女孩接受了两年的苯巴比妥治疗。家族所有成员的神经发育均正常。在低剂量苯巴比妥治疗下,我们的患者至今未再发作。

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