Váradi V, Nagy A, György I, Machay T, Papp Z
Debreceni Orvostudományi Egyetem, Gyermekklinika, Budapest.
Orv Hetil. 1995 Feb 19;136(8):401-5.
Authors reported about their experiences with newborn infants, who had transient myasthenia gravis; one disease developed in the fetal, others 10 in the early neonatal age. Direct correlation was found between the development of maternal polyhydramnios and the severity symptoms in newborns: risk of neonatal myasthenia gravis increased at these infants. Specific treatment included blood exchange transfusions and pyridostigmin (Mestinon) medication for 2-10 weeks. Five transient myasthenia gravis responded readily to blood exchange transfusions. Authors pointed out that in the early neonatal period the aetiology of an obscure respiratory inadequacy and hypoventilation might be regarded as transient myasthenia gravis.
作者报告了他们对患有短暂性重症肌无力的新生儿的治疗经验;其中1例在胎儿期发病,另外10例在新生儿早期发病。发现孕妇羊水过多的情况与新生儿症状的严重程度之间存在直接关联:这些婴儿患新生儿重症肌无力的风险增加。具体治疗包括进行换血输血以及使用吡啶斯的明(美斯的明)药物治疗2至10周。5例短暂性重症肌无力患者对换血输血反应良好。作者指出,在新生儿早期,不明原因的呼吸功能不全和通气不足的病因可能被视为短暂性重症肌无力。