Urwijitaroon Y, Teawpatanataworn S, Kitjareontarm A
Department of Clinical Immunology, Faculty of Associated Medical Sciences, Khon Kaen University, Thailand.
Southeast Asian J Trop Med Public Health. 1993;24 Suppl 1:180-2.
The prevalence of cytomegalovirus antibody was studied in sera of 359 Northeastern blood donors with an age range of 17-59 years by ELISA for anti-CMV total antibody (anti-CMV). Anti-CMV was detected in 93.31% (335/359) of blood donors. The prevalence in males was 91.53% (227 in 248) while female donors showed 97.30% (108 in 111) positive for anti-CMV. The results demonstrated no statistical difference between sex and age. One-hundred and eighty serum samples with positive anti-CMV were reexamined for anti-CMV IgM antibody. Only one sample was found to be positive. This study suggested that CMV seronegative blood supply was very limited. Therefore leukocyte-depleted blood should be the method of choice for prevention of post-transfusion CMV infections in high risk recipients.
采用酶联免疫吸附测定法（ELISA）检测抗巨细胞病毒（CMV）总抗体，对年龄在17至59岁之间的359名东北献血者的血清进行巨细胞病毒抗体流行率研究。在93.31%（335/359）的献血者中检测到抗CMV。男性的流行率为91.53%（248人中227人），而女性献血者抗CMV阳性率为97.30%（111人中108人）。结果表明性别和年龄之间无统计学差异。对180份抗CMV阳性的血清样本重新检测抗CMV IgM抗体。仅发现1份样本呈阳性。本研究提示CMV血清阴性供血非常有限。因此，去除白细胞的血液应作为预防高危受血者输血后CMV感染的首选方法。
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