Chuansumrit A, Pandhawong S, Tardtong P, Isarangkura P
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Southeast Asian J Trop Med Public Health. 1993;24 Suppl 1:198-200.
This study comments on safe blood components prepared for a 6 year old boy with hemophilia A (F VIII:C 1.8%). He has required blood transfusion since 10 months of age and started home therapy since 3 years of age. The utilized blood components were fresh dry plasma (FDP) prepared from 8-10 selected donors who were in good health and had no risk of blood-transmitted diseases. They were parents, relatives and friends with the age ranging from 30-45 years old. The FDP would be used after the donors had at least two subsequent negative tests for anti-HIV. In addition, cryoprecipitate collected from parents by plasmapheresis was started in 1990. Twelve to fifteen bags of cryoprecipitate were collected each plasmapheresis. The blood components prepared from the selected donors is an additional management to obtain the better quality of blood. Moreover, the role of parents taking the major responsibility in the recruitment of donors will minimize the shortage of blood donors.
本研究对为一名6岁血友病A男孩（F VIII:C 1.8%）制备的安全血液成分进行了评论。他自10个月大起就需要输血，3岁起开始家庭治疗。所使用的血液成分是从8 - 10名健康且无血液传播疾病风险的选定供体中制备的新鲜冻干血浆（FDP）。他们是年龄在30 - 45岁之间的父母、亲属和朋友。在供体至少两次后续抗HIV检测呈阴性后，才会使用FDP。此外，1990年开始通过血浆置换从父母处采集冷沉淀。每次血浆置换收集12至15袋冷沉淀。从选定供体制备的血液成分是为获得更高质量血液而采取的额外管理措施。此外，父母在招募供体方面承担主要责任的作用将最大限度地减少献血者短缺的情况。
