Murray R G, Lorimer A R, Dunn F G, Macfarlane P W, Hutton I, Lawrie T D
Br Heart J. 1976 Aug;38(8):773-8. doi: 10.1136/hrt.38.8.773.
The computer-analysed 3 orthogonal lead system ("3-lead ECG") provides a rapid and consistent interpretation of the electrocardiogram. In 102 patients undergoing selective coronary arteriography, the ability of such a system to predict the presence of absence of coronary artery disease and the site of myocardial ischaemia was compared with that of the conventional scalar electrocardiogram interpreted by cardiologists ("12-lead ECG"). Each system predicted the site of myocardial ischaemia with equal accuracy. The 3-lead ECG was a more sensitive index (3-lead ECG sensitivity=77%; 12-lead ECG sensitivity=70%) but less specific (3-lead ECG specificity=74%; 12-lead ECG specificity=78%). In coronary artery disease, the predictive "index of merit" for the 3-lead ECG was 0-51, compared with 0-48 for the 12-lead ECG. These results provide further justification for the routine use of the 3 orthogonal lead electrocardiogram.
计算机分析的3导联系统（“3导联心电图”）能快速、一致地解读心电图。在102例接受选择性冠状动脉造影的患者中，将该系统预测冠状动脉疾病的有无及心肌缺血部位的能力与心脏病专家解读的传统单导联心电图（“12导联心电图”）进行了比较。每个系统预测心肌缺血部位的准确性相同。3导联心电图是一个更敏感的指标（3导联心电图敏感性=77%；12导联心电图敏感性=70%），但特异性较低（3导联心电图特异性=74%；12导联心电图特异性=78%）。在冠状动脉疾病中，3导联心电图的预测“优点指数”为0.51，而12导联心电图为0.48。这些结果为常规使用3导联正交心电图提供了进一步的依据。
