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遵守变应原免疫疗法方案。

Compliance with an allergen immunotherapy regime.

作者信息

Tinkelman D, Smith F, Cole W Q, Silk H J

机构信息

Atlanta Allergy Clinic, GA 30328.

出版信息

Ann Allergy Asthma Immunol. 1995 Mar;74(3):241-6.

PMID:7889380
Abstract

BACKGROUND

Compliance with an allergy immunotherapy regimen is obviously the difference between a potentially successful or unsuccessful outcome.

OBJECTIVE

The purpose of this study was to assess retrospectively compliance of patients receiving immunotherapy in a private allergy practice.

METHODS

The study evaluated retrospectively patient compliance with prescribed allergy injections for a private practice in Atlanta, Georgia. Patients who ordered allergy extract material for their injection immunotherapy program during an 18-month period served as the index population for this study. For the purposes of this study, noncompliance was defined as stopping the allergy injection program without the approval of the prescribing physician. Part of this investigation was to determine whether there were compliance differences between those who received their allergy injections within the confines of the clinic and those who received their injections at outside physician offices. A 12-month period of review was considered adequate to monitor compliance because of the 12-month expiration date placed on the allergy extracts.

RESULTS

There was a noncompliance rate of 10: 77% for those who received their injections within the clinic. This contrasted with the noncompliance rate in the remote population of 34.82%. The difference between these two groups was statistically significant (P < .01). There were no statistical differences with respect to sex or diagnostic category. Significant differences were found between age groups in those receiving injections within or outside the clinic.

CONCLUSIONS

There is a much higher rate of noncompliance in those who receive their injections in facilities outside the allergist's office. This suggests that to ensure better compliance either individuals should either be encouraged to receive their injections at the allergist's office, or better communications should be established between the referring allergist and the nonallergy physicians who are administering the injections.

摘要

背景

遵循过敏免疫疗法方案显然是决定治疗结果可能成功或失败的关键因素。

目的

本研究旨在回顾性评估在一家私人过敏诊所接受免疫疗法的患者的依从性。

方法

该研究回顾性评估了佐治亚州亚特兰大一家私人诊所患者对规定的过敏注射治疗的依从性。在18个月期间订购过敏提取物用于注射免疫疗法的患者作为本研究的指标人群。在本研究中,不依从被定义为未经开处方医生批准就停止过敏注射治疗方案。本调查的一部分是确定在诊所内接受过敏注射的患者与在外部医生办公室接受注射的患者之间是否存在依从性差异。由于过敏提取物的有效期为12个月,因此认为12个月的回顾期足以监测依从性。

结果

在诊所内接受注射的患者的不依从率为10.77%。相比之下,偏远地区人群的不依从率为34.82%。这两组之间的差异具有统计学意义(P < .01)。在性别或诊断类别方面没有统计学差异。在诊所内或诊所外接受注射的患者的年龄组之间存在显著差异。

结论

在过敏专科医生办公室以外的机构接受注射的患者的不依从率要高得多。这表明,为确保更好的依从性,要么应鼓励患者在过敏专科医生办公室接受注射,要么应在转诊的过敏专科医生与进行注射的非过敏专科医生之间建立更好的沟通。

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