Cytogenetic and FISH investigations on tetrasomy 8 in ANLL.
作者信息
La Starza R, Crescenzi B, Matteucci C, Martelli M F, Mecucci C
机构信息
Ematologia e Immunologia Clinica, Università degli Studi di Perugia, Policlinico Monteluce, Italy.
出版信息
Cancer Genet Cytogenet. 1995 Feb;79(2):182-5. doi: 10.1016/0165-4608(94)00120-z.
PMID:7889517
Abstract
Two patients with "de novo" ANLL and tetrasomy of chromosome 8 at diagnosis are described. A mosaic karyotype with coexistence of normal metaphases was found in both cases. Trisomy 8 was also present in one metaphase of the first patient. Fluorescent in situ hybridization with a centromeric probe from chromosome 8 was applied in the second case, confirming the presence of a minor population with trisomy 8 in interphase nuclei.
摘要
Zotero 插件