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三叉神经痛的微血管减压术:一项批判性重新评估

Microvascular decompression for trigeminal neuralgia: a critical reappraisal.

作者信息

Walchenbach R, Voormolen J H, Hermans J

机构信息

Department of Neurosurgery, State University Leiden, The Netherlands.

出版信息

Clin Neurol Neurosurg. 1994 Nov;96(4):290-5. doi: 10.1016/0303-8467(94)90116-3.

Abstract

The results of posterior fossa explorations for trigeminal neuralgia over the period 1980-1990 in 58 patients and in 59 procedures were studied retrospectively. In 51 procedures vascular compression was treated by microvascular decompression (MVD). In the absence of such a compression, partial sensory rhizotomy (PSR) was performed in 5 cases and only adhesiolysis of thickened arachnoidea in 2 cases. In one additional case the procedure was terminated prematurely due to the development of cerebellar edema. Two months postoperatively a good or fair result was obtained in 80% of the procedures. At long-term follow-up (mean 77.3 months, range 8-146 months), a good or fair result was maintained in 71%. There was no significant difference in outcome between the MVD group and the other procedures, or between the three groups formed according to the type of vascular compression. However, in the group of 10 patients with a history of a procedure affecting the trigeminal ganglion or nerve root the result was worse. In the group of 41 MVD patients rendered free of pain at 2 months postoperatively, 8 patients perceived a recurrence. The annual recurrence rate was calculated to be 2.6%. There was no mortality in this series but the morbidity rate was 22% including 1.7% persistent neurological deficit. Compared to the literature results of percutaneous controlled differential thermocoagulation (PCDT), the recurrence and failure rates in the present series appear to be more or less the same. As neither of the two is an unequivocally more effective treatment, we are of the opinion that the less invasive procedure should be preferred.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对1980年至1990年间58例患者接受的59次三叉神经痛后颅窝探查结果进行了回顾性研究。在51次手术中,采用微血管减压术(MVD)治疗血管压迫。在不存在这种压迫的情况下,5例患者进行了部分感觉神经根切断术(PSR),2例仅进行了增厚蛛网膜粘连松解术。在另外1例中,由于小脑水肿的出现,手术提前终止。术后两个月,80%的手术获得了良好或尚可的结果。在长期随访(平均77.3个月,范围8 - 146个月)中,71%的患者维持了良好或尚可的结果。MVD组与其他手术组之间,或根据血管压迫类型形成的三组之间,结果无显著差异。然而,在有影响三叉神经节或神经根手术史的10例患者组中,结果较差。在术后2个月无痛的41例MVD患者组中,8例患者出现复发。计算得出年复发率为2.6%。本系列无死亡病例,但发病率为22%,包括1.7%的持续性神经功能缺损。与经皮可控性微分热凝术(PCDT)的文献结果相比,本系列的复发率和失败率似乎大致相同。由于这两种方法都不是明确更有效的治疗方法,我们认为应首选侵入性较小的手术。(摘要截短于250字)

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