Lelaidier C, de Ziegler D, Freitas S, Olivennes F, Hazout A, Frydman R
Department of Obstetrics and Gynecology, Hôpital A. Bećlere, Clamart, France.
Fertil Steril. 1995 Apr;63(4):919-21. doi: 10.1016/s0015-0282(16)57503-7.
To determine the implantation rates of cryopreserved blastocysts using controlled E2 and P replacement cycles in women with functioning ovaries.
Retrospective clinical study.
University teaching hospital.
Infertile women with cryopreserved blastocysts obtained from previous IVF attempts.
Exogenous E2 was administered orally from cycle day 1 and P was started transvaginally from day 15. Blastocysts were transferred on the 5th day of endometrial exposure to P (day 19).
Blastocyst implantation rate and pregnancy rate (PR).
Ninety-eight percent of blastocysts survived thawing: 67 were transferred in 42 women. Eight pregnancies occurred giving a PR of 19% per ET and 11.9% per blastocyst.
The high PR observed after transferring blastocysts on the 5th day of endometrial exposure to P in controlled E2 and P replacement cycles speaks for a forward slide of the window of transfer in case of blastocysts.
确定在卵巢功能正常的女性中，使用控制性雌二醇（E2）和孕酮（P）替代周期移植冷冻囊胚的着床率。
回顾性临床研究。
大学教学医院。
既往体外受精（IVF）尝试中获得冷冻囊胚的不孕女性。
从周期第1天开始口服外源性E2，从第15天开始经阴道给予P。在子宫内膜暴露于P的第5天（第19天）移植囊胚。
囊胚着床率和妊娠率（PR）。
98%的囊胚解冻后存活：42名女性中移植了67个囊胚。发生了8次妊娠，每次胚胎移植（ET）的PR为19%，每个囊胚的PR为11.9%。
在控制性E2和P替代周期中，在子宫内膜暴露于P的第5天移植囊胚后观察到的高PR表明，对于囊胚而言，移植窗向前推移。
