Adimora A A, Sparling P F, Cohen M S
Division of Infectious Diseases, Department of Medicine, UNC School of Medicine, Chapel Hill 27599-7030.
Infect Dis Clin North Am. 1994 Dec;8(4):859-76.
Sexually transmitted diseases (STDs) can substantially increase the morbidity and mortality of exposed adults and children. Despite the advent of new antibiotics and focus on behavioral interventions such as condom use, attempts to limit the spread of STDs have been largely unsuccessful. Vaccines have received increasing attention as a potential strategy for STD control. This article focuses on the current status of vaccine research for five classic STDs: gonorrhea, genital herpes, syphilis, chancroid, and chlamydia.
性传播疾病(STDs)会显著增加接触到的成年人和儿童的发病率和死亡率。尽管出现了新的抗生素,且人们也注重诸如使用避孕套等行为干预措施,但限制性传播疾病传播的努力在很大程度上并不成功。疫苗作为一种控制性传播疾病的潜在策略,受到了越来越多的关注。本文重点介绍了针对五种经典性传播疾病:淋病、生殖器疱疹、梅毒、软下疳和衣原体感染的疫苗研究现状。