Barbosa-Cesnik C T, Gerbase A, Heymann D
World Health Organisation, Office of HIV, AIDS and Sexually Transmitted Diseases (ASD), Geneva, Switzerland.
Genitourin Med. 1997 Oct;73(5):336-42. doi: 10.1136/sti.73.5.336.
To describe the role and current status of vaccine research against sexually transmitted diseases (STDs).
The available literature was reviewed with particular emphasis on bacterial STDs.
Strategic approaches to possible implementation of STD vaccine programmes were analysed. The status of vaccines against bacterial STDs (syphilis, chancroid, gonorrhoea, and chlamydia) is described in detail.
The development of safe and effective STD vaccines offers a potent tool for the control of STDs, including direct and indirect prevention of HIV infection. Future priorities should be in the development of vaccines against gonorrhoea, chlamydia, and syphilis. When such vaccines become available, caution should be exercised to ensure that they do not interfere with the effectiveness of other prevention programmes.
描述性传播疾病(STD)疫苗研究的作用和现状。
回顾现有文献,特别关注细菌性性传播疾病。
分析了性传播疾病疫苗计划可能实施的战略方法。详细描述了针对细菌性性传播疾病(梅毒、软下疳、淋病和衣原体感染)的疫苗现状。
开发安全有效的性传播疾病疫苗为控制性传播疾病提供了有力工具,包括直接和间接预防艾滋病毒感染。未来的重点应放在开发针对淋病、衣原体感染和梅毒的疫苗上。当此类疫苗可用时,应谨慎行事,以确保它们不会干扰其他预防计划的有效性。