一种新的实验模型：用于脊髓损伤后继发性变化的进一步研究。
A new experimental model: for further investigation of the secondary changes following spinal cord injury.
作者信息
Colak A, Nurlu G, Açikgöz B, Ozcan O E, Aydim E
机构信息
Department of Neurosurgery, Hacettepe University, Ankara, Turkey.
出版信息
J Neurosurg Sci. 1994 Jun;38(2):111-6.
To investigate the pathophysiology of spinal trauma, several experimental models have been used. In this study, the authors present a new experimental model for further investigation of secondary damage following spinal injury. Nd:YAG laser irradiation was applied to the spinal cord of guinea pigs to produce an injury. A 30 Watt (20 Joule) laser produced paraparesis. The injury was evaluated with evoked potentials, lipid peroxidation values, and histopathological examination.
为了研究脊柱创伤的病理生理学，已经使用了几种实验模型。在本研究中，作者提出了一种新的实验模型，用于进一步研究脊髓损伤后的继发性损伤。用钕：钇铝石榴石激光照射豚鼠脊髓以造成损伤。一台30瓦（20焦耳）的激光导致了双下肢轻瘫。通过诱发电位、脂质过氧化值和组织病理学检查对损伤进行评估。
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