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[石棉沉着病中气道阻塞的发生率]

[The incidence of airway obstruction in asbestosis].

作者信息

Niebecker M, Smidt U, Gasthaus L, Worth G

机构信息

Institut für Arbeitsmedizin, Moers.

出版信息

Pneumologie. 1995 Jan;49(1):20-6.

PMID:7892153
Abstract

In a retrospective study we have examined the clinical data, radiographs and lung function of 382 men with an asbestosis, established by occupational exposure and typical findings in the chest x-ray, according to the ILO-classification from 1980. In particular the correlation between airflow limitation, asbestosis of lung and/or pleura and smoking habits was investigated. However the mean values of parameters were only marginally pathological, lifetime non-smokers showed a significant increase of airway obstruction in connection with advanced radiologic alterations. Current smokers with medium or severe radiologic alterations had on average a significant airway obstruction which was more pronounced in cases with pleural lesions than with pulmonary alterations. In conclusion an additive or even multiplying effect of smoking and asbestosis has to be considered.

摘要

在一项回顾性研究中,我们检查了382名石棉沉着病男性患者的临床数据、X光片和肺功能。这些患者的石棉沉着病是由职业暴露以及胸部X光片的典型表现所确诊的,依据的是1980年的国际劳工组织(ILO)分类标准。特别对气流受限、肺和/或胸膜的石棉沉着病与吸烟习惯之间的相关性进行了研究。然而,各项参数的平均值仅略呈病态,终生不吸烟者在出现晚期放射学改变时气道阻塞显著增加。有中度或重度放射学改变的现吸烟者平均存在明显的气道阻塞,在有胸膜病变的病例中比有肺部病变的病例更为明显。总之,必须考虑吸烟与石棉沉着病之间的相加甚至相乘效应。

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